Koji Osuka Selected Research

Chronic Subdural Hematoma

1/2021	Sequential Expression of Chemokines in Chronic Subdural Hematoma Fluids after Trepanation Surgery.
12/2020	Expression of Angiopoietins and Angiogenic Signaling Pathway Molecules in Chronic Subdural Hematomas.
1/2020	Expression of high mobility group B1 and toll-like receptor-nuclear factor κB signaling pathway in chronic subdural hematomas.
10/2018	Expressions of Eotaxin-3, Interleukin-5, and Eosinophil-Derived Neurotoxin in Chronic Subdural Hematoma Fluids.
11/2017	Expression of Caspase Signaling Components in the Outer Membranes of Chronic Subdural Hematomas.
1/2017	Activation of Nuclear Factor-kappa B in Endothelial Cells of Chronic Subdural Hematoma Outer Membranes.
1/2017	Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas.
7/2016	Activation of Signal Transducer and Activator of Transcription 3 in Endothelial Cells of Chronic Subdural Hematoma Outer Membranes.
7/2015	Expression of Mitogen-Activated Protein Kinases in Chronic Subdural Hematoma Outer Membranes.
8/2014	Eotaxin-3 activates the Smad pathway through the transforming growth factor beta 1 in chronic subdural hematoma outer membranes.

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Koji Osuka Research Topics

Disease

12	Chronic Subdural Hematoma 01/2021 - 06/2011
12	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2021 - 02/2006
6	Brain Ischemia (Cerebral Ischemia) 12/2018 - 11/2004
4	Inflammation (Inflammations) 01/2021 - 01/2016
4	Intervertebral Disc Displacement (Herniated Disc) 05/2014 - 04/2012
3	Pain (Aches) 01/2020 - 01/2014
3	Ischemia 12/2018 - 09/2002
3	Pathologic Constriction (Stenosis) 10/2015 - 04/2012
3	Intracranial Vasospasm 08/2014 - 09/2011
3	Spinal Cord Injuries (Spinal Cord Injury) 02/2010 - 02/2006
2	Brain Injuries (Brain Injury) 01/2020 - 08/2015
2	Arthritis (Polyarthritis) 01/2008 - 04/2002
1	Hemifacial Spasm 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Contracture 01/2020
1	Hyperalgesia 01/2020
1	Muscular Atrophy (Muscle Atrophy) 01/2020
1	Cognitive Dysfunction 12/2018
1	Hypertrophy 03/2017
1	Radiculopathy (Radiculopathy, Cervical) 05/2015
1	Hematoma 12/2012
1	Osteophyte 10/2012
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2012
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 11/2011
1	Hypothermia 11/2011
1	Ischemic Stroke 11/2004
1	Infections 04/2002
1	Rheumatoid Arthritis 04/2002
1	Osteoarticular Tuberculosis 04/2002

Drug/Important Bio-Agent (IBA)

11	CytokinesIBA 10/2018 - 02/2006
6	Interleukin-6 (Interleukin 6)IBA 01/2017 - 02/2006
4	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 12/2018 - 09/2002
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2004
3	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 08/2015 - 09/2002
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 04/2012 - 05/2008
2	ChemokinesIBA 01/2021 - 01/2016
2	Chemotactic FactorsIBA 01/2021 - 01/2016
2	Chemokine CCL26IBA 10/2018 - 08/2014
2	Neuroprotective AgentsIBA 08/2015 - 11/2011
2	Mitogen-Activated Protein KinasesIBA 07/2015 - 09/2007
2	Calcium-Calmodulin-Dependent Protein KinasesIBA 10/2013 - 11/2011
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2012 - 11/2004
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2012 - 05/2010
1	AngiopoietinsIBA 12/2020
1	CpCpIBA 01/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020
1	Complement C5 (Complement 5)IBA 01/2020
1	AntibodiesIBA 01/2020
1	AcetoneIBA 01/2020
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 12/2018
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2018
1	Interleukin-5 (Interleukin 5)IBA 10/2018
1	Eosinophil-Derived NeurotoxinIBA 10/2018
1	CaspasesIBA 11/2017
1	NF-kappa B (NF-kB)IBA 01/2017
1	Janus KinasesIBA 01/2017
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 07/2016
1	Indicators and Reagents (Reagents)IBA 08/2015
1	Transforming Growth Factor beta (TGF-beta)IBA 08/2014
1	TitaniumIBA 01/2014
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2012
1	AdiponectinIBA 04/2012
1	STAT1 Transcription FactorIBA 12/2011
1	EnzymesIBA 11/2011
1	CalciumIBA 11/2011
1	Cytokine Receptor gp130IBA 09/2011
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 06/2011
1	Taurine FDA Link 02/2010
1	JNK Mitogen-Activated Protein KinasesIBA 09/2007
1	Nitric Oxide Synthase (NO Synthase)IBA 11/2004
1	Rifampin (Rifampicin)FDA LinkGeneric 04/2002
1	Pyrazinamide FDA LinkGeneric 04/2002
1	Prednisolone (Predate)FDA LinkGeneric 04/2002
1	Isoniazid (Ftivazide)FDA LinkGeneric 04/2002
1	Ethambutol (Myambutol)FDA LinkGeneric 04/2002

Therapy/Procedure

4	Decompression 01/2021 - 04/2012
2	Trephining 01/2021 - 01/2017
1	Microvascular Decompression Surgery 01/2021
1	Muscle Denervation 10/2015
1	Injections 01/2014
1	Operative Surgical Procedures 10/2012
1	Arthroplasty 01/2008
1	Synovectomy 04/2002
1	Curettage 04/2002